Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.34 |
| ▸ | CTSG | P08311 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575092 | 0.89 | CTSG (0.43) | TP53POLBCTSGCMA1 | |
| SCHEMBL8575472 | 0.88 | PTGER3 (0.38) | PTGER3PTGER2PPARDPPARAFFAR4 | |
| Hydrochloric Acid SCHEMBL8575626 | 0.88 | CTSG (0.42) | TP53POLBCTSGCMA1 | |
| SCHEMBL8575529 | 0.84 | PTGER4 (0.37) | PTGER3PTGER2TP53PPARDPPARA | |
| SCHEMBL8572789 | 0.83 | PTGER4 (0.40) | TP53POLBCTSGCMA1ITGB3 | |
| SCHEMBL8573785 | 0.82 | FFAR4 (0.39) | PTGER3PTGER2TP53FFAR4 | |
| SCHEMBL8572958 | 0.81 | GRIN1 (0.40) | POLBHPGD | |
| SCHEMBL8875629 | 0.79 | MEN1 (0.43) | CTSGCMA1 | |
| SCHEMBL8416012 | 0.79 | PTGER3 (0.35) | PTGER3PTGER2PPARDFFAR4 | |
| SCHEMBL8573857 | 0.78 | PTPN1 (0.35) | PPARDPPARAPOLBITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |