Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181278 | 0.98 | CYP3A4 (0.35) | CYP3A4LMNAKDM4EMAPTALOX15 | |
| SCHEMBL18493238 | 0.79 | TAAR1 (0.39) | CYP3A4LMNAKDM4EMAPTALOX15 | |
| SCHEMBL30518068 | 0.79 | SLC6A2 (0.42) | LMNAKDM4EMAPTALDH1A1HTR2A | |
| SCHEMBL290984 | 0.76 | LMNA (0.46) | CYP3A4LMNAKDM4EMAPTCYP2C19 | |
| SCHEMBL11324526 | 0.76 | LMNA (0.42) | CYP3A4LMNAKDM4ECYP2C19TSHR | |
| SCHEMBL11453525 | 0.75 | TP53 (0.42) | LMNAMAPTTSHRALDH1A1HTR2A | |
| Hydrochloric Acid SCHEMBL1752733 | 0.74 | LMNA (0.45) | CYP3A4LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL16191759 | 0.71 | CYP3A4 (0.34) | CYP3A4LMNAKDM4EMAPTALOX15 | |
| SCHEMBL988241 | 0.71 | SIGMAR1 (0.39) | LMNACYP2C19ALDH1A1HTR2AHRH1 | |
| SCHEMBL5696258 | 0.71 | CYP2C19 (0.39) | CYP3A4LMNAKDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11080166-A | — | — | None | — | — | JP | disclosed |
| JP-H1180166-A | PRODUCTION OF TRIPHENYLBORON | YOSHITOMI FINE CHEM KK | 1999-03-26 | — | — | JP | disclosed |