Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13710706 | 0.78 | CES1 (0.48) | MDM2TDP1L3MBTL1CES1CES2 | |
| SCHEMBL17238644 | 0.78 | MDM2 (0.48) | MDM2TDP1L3MBTL1CES1CES2 | |
| SCHEMBL10644287 | 0.77 | PGR (0.49) | MDM2TDP1L3MBTL1CES1CES2 | |
| SCHEMBL8898354 | 0.76 | MAPK1 (0.48) | MDM2TDP1L3MBTL1CES1CES2 | |
| SCHEMBL3810221 | 0.76 | PGR (0.52) | MDM2TDP1L3MBTL1CES1CES2 | |
| SCHEMBL5377464 | 0.76 | L3MBTL1 (0.52) | MDM2TDP1L3MBTL1CES1CES2 | |
| SCHEMBL1128352 | 0.74 | MDM2 (0.66) | MDM2MAPK1ALDH1A1MAPTMEN1 | |
| SCHEMBL28373292 | 0.73 | CES1 (0.41) | MDM2TDP1L3MBTL1CES1CES2 | |
| SCHEMBL9019293 | 0.73 | MDM2 (0.41) | MDM2TDP1L3MBTL1CES1CES2 | |
| SCHEMBL5274104 | 0.73 | TDP1 (0.52) | MDM2TDP1L3MBTL1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015572-A1 | A COMPOSITION COMPRISING AN IMMOBILISED, ACYLATED PEPTIDE | AKZO NOBEL N.V. (NL) | 1998-04-16 | — | — | WO | disclosed |