Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147694 | 0.79 | ALKBH5 (0.43) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL31468333 | 0.79 | PGR (0.47) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL7030603 | 0.77 | MDM2 (0.59) | MDM2ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL9019110 | 0.77 | ALKBH5 (0.46) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL9854646 | 0.76 | NR4A2 (0.44) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL13710706 | 0.74 | CES1 (0.48) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL1224747 | 0.73 | TDP1 (0.44) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL10644287 | 0.73 | PGR (0.49) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL8575631 | 0.73 | MDM2 (0.44) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL9018972 | 0.72 | NPC1 (0.42) | MDM2TDP1L3MBTL1LMNACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434940-B1 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID CO (US) | 1996-05-29 | — | — | EP | claimed |
| US-5399716-A | N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-03-21 | — | — | US | claimed |
| EP-0434940-A2 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | claimed |