Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157863 | 0.87 | ALDH1A1 (0.48) | OGG1CA12MAPTCA1ALDH1A1 | |
| SCHEMBL11068295 | 0.80 | OGG1 (0.67) | OGG1CES2CES1CA12MMP2 | |
| SCHEMBL1982518 | 0.80 | POLB (0.68) | OGG1CES2CES1MAPTALDH1A1 | |
| SCHEMBL13481186 | 0.80 | POLB (0.68) | OGG1CES2CES1MAPTALDH1A1 | |
| SCHEMBL8575405 | 0.80 | OGG1 (0.67) | OGG1CES2CES1CA12MMP2 | |
| SCHEMBL7667888 | 0.78 | GFER (0.60) | CES2CA12CA14MAPTCA1 | |
| Hydrochloric Acid SCHEMBL27743016 | 0.78 | OGG1 (0.64) | OGG1CES2CES1CA12MMP2 | |
| SCHEMBL992073 | 0.78 | TSHR (0.60) | CES2CES1CA12CA14CA1 | |
| SCHEMBL8606592 | 0.78 | ALDH1A1 (0.64) | CES2CES1MAPTCA1CA2 | |
| SCHEMBL1883228 | 0.76 | MEN1 (0.55) | CES2CES1CA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015541-A1 | NOVEL ISOXAZOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS | EGIS Gyógyszergyár Rt. (HU) | 1998-04-16 | — | — | WO | disclosed |