Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157863 | 0.89 | ALDH1A1 (0.48) | ALOX15CA1CA12CA9ALDH1A1 | |
| SCHEMBL809769 | 0.82 | ALOX15 (0.61) | TSHRALOX15CA1CA12CA9 | |
| SCHEMBL7667888 | 0.80 | GFER (0.60) | CA1CA2CA12CA3TYR | |
| SCHEMBL8606592 | 0.80 | ALDH1A1 (0.64) | TSHRALOX15CA1CA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27790926 | 0.80 | ALOX15 (0.58) | TSHRALOX15CA1CA12CA9 | |
| SCHEMBL9849004 | 0.79 | RAB9A (0.62) | ALOX15SRD5A2CA1CA12CA9 | |
| SCHEMBL11705058 | 0.79 | TSHR (0.67) | TSHRTP53ALOX15SRD5A2CA1 | |
| SCHEMBL1883228 | 0.78 | MEN1 (0.55) | CA1CA2MITFSMN1; SMN2CES2 | |
| SCHEMBL8575647 | 0.78 | OGG1 (0.61) | TP53CA1CA2CA12CA14 | |
| SCHEMBL29022127 | 0.78 | PARP10 (0.48) | TSHRCA1CA2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010014-A1 | CHROMENE DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-01-27 | — | — | WO | disclosed |
| EP-2277882-A1 | Pipéridinic compounds, process for their préparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-01-26 | — | — | EP | disclosed |
| CN-1441637-A | Compositions for repelling crawling insects | BAYER AG (DE) | 2003-09-10 | — | — | CN | disclosed |