Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 8/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 4/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21286395 | 0.85 | ABCB1 (0.38) | ABCB1SRCPARP1BRD4IDO1 | |
| SCHEMBL29985450 | 0.85 | ABCB1 (0.38) | ABCB1SRCPARP1BRD4IDO1 | |
| SCHEMBL3948504 | 0.85 | ABCB1 (0.38) | ABCB1SRCPARP1BRD4IDO1 | |
| SCHEMBL8568862 | 0.80 | NR1H2 (0.39) | ABCB1SRCPARP1MEN1KMT2A | |
| SCHEMBL8568867 | 0.80 | NR1H2 (0.39) | ABCB1SRCPARP1MEN1KMT2A | |
| SCHEMBL3952747 | 0.80 | BRD4 (0.39) | ABCB1SRCBRD4 | |
| SCHEMBL7807928 | 0.80 | BRD4 (0.39) | ABCB1SRCBRD4 | |
| SCHEMBL19674208 | 0.79 | HSD17B10 (0.40) | SRCBRD4IDO1MEN1KMT2A | |
| SCHEMBL8572979 | 0.79 | CYP1A2 (0.43) | SRCBRD4IDO1MEN1KMT2A | |
| SCHEMBL3947235 | 0.79 | CYP1A2 (0.43) | SRCBRD4IDO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |