Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.59 |
| ▸ | CTSK | P43235 | 7/20 | 0.59 |
| ▸ | CTSB | P07858 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291961 | 1.00 | CTSS (0.59) | CTSSCTSKCTSBCTSLEPHX2 | |
| SCHEMBL11022599 | 0.91 | BCL2 (0.58) | CTSSCTSKCTSBCTSLEPHX2 | |
| SCHEMBL8572724 | 0.88 | REN (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL8572729 | 0.88 | REN (0.65) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL11100198 | 0.87 | ABCB1 (0.52) | CTSSCTSKCTSBCTSLEPHX2 | |
| SCHEMBL11382926 | 0.87 | CTSS (0.58) | CTSSCTSKCTSBCTSLEPHX2 | |
| SCHEMBL11382927 | 0.87 | CTSS (0.58) | CTSSCTSKCTSBCTSLEPHX2 | |
| SCHEMBL28122853 | 0.86 | CTSS (0.62) | CTSSCTSKCTSBCTSLEPHX2 | |
| SCHEMBL28122855 | 0.86 | CTSS (0.62) | CTSSCTSKCTSBCTSLEPHX2 | |
| SCHEMBL16459752 | 0.86 | CTSS (0.68) | CTSSCTSKCTSBCTSLEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853713-A | Biologically compatible linear block copolymers of polyalkylene oxide and peptide units | STERLING WINTHROP INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5618528-A | Biologically compatible linear block copolymers of polyalkylene oxide and peptide units | STERLING WINTHROP INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0748226-A1 | BLOCK COPOLYMERS | NYCOMED IMAGING AS (NO) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995022991-A2 | BLOCK COPOLYMERS | NYCOMED IMAGING AS (NO) | 1995-08-31 | — | — | WO | disclosed |
| US-5166136-A | SPIROLACTAM CONTAINING PEPTIDES | GLAXO GROUP LIMITED (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0360390-A1 | Spirolactam derivatives | GLAXO GROUP LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |