Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | YAP1 | P46937 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291961 | 0.91 | CTSS (0.59) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL8575674 | 0.91 | CTSS (0.59) | RENCTSSCTSLCTSBCTSK | |
| SCHEMBL10784370 | 0.90 | ITGB3 (0.56) | HDAC8ITGB3ITGA2BCTSSGPR34 | |
| SCHEMBL7523637 | 0.87 | BCL2 (0.64) | BCL2PTPN1HDAC8YAP1ITGB3 | |
| SCHEMBL9752771 | 0.87 | BCL2 (0.64) | BCL2PTPN1HDAC8YAP1ITGB3 | |
| SCHEMBL6161729 | 0.87 | BCL2 (0.64) | BCL2PTPN1HDAC8YAP1ITGB3 | |
| SCHEMBL9752770 | 0.87 | BCL2 (0.64) | BCL2PTPN1HDAC8YAP1ITGB3 | |
| SCHEMBL3500186 | 0.87 | BCL2 (0.64) | BCL2PTPN1HDAC8YAP1ITGB3 | |
| SCHEMBL3350988 | 0.87 | BCL2 (0.64) | BCL2PTPN1HDAC8YAP1ITGB3 | |
| SCHEMBL18025361 | 0.86 | BCL2 (0.63) | BCL2PTPN1HDAC8YAP1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034259-B1 | PEPTIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS OR DIAGNOSTIC AGENTS CONTAINING THEM | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1985-06-12 | — | — | EP | disclosed |
| EP-0034260-B1 | PEPTIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS OR DIAGNOSTIC AGENTS CONTAINING THEM | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1983-07-20 | — | — | EP | disclosed |
| EP-0034260-A1 | Peptides, process for their preparation and medicaments or diagnostic agents containing them | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1981-08-26 | — | — | EP | disclosed |