Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568241 | 0.84 | LOXL2 (0.52) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 | |
| SCHEMBL17857810 | 0.84 | TSHR (0.72) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 | |
| SCHEMBL10452156 | 0.83 | TSHR (0.59) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 | |
| SCHEMBL29904577 | 0.83 | TSHR (0.82) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 | |
| SCHEMBL5780447 | 0.83 | TSHR (0.55) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 | |
| SCHEMBL17474257 | 0.83 | TSHR (0.82) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 | |
| SCHEMBL16603419 | 0.83 | TSHR (0.82) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 | |
| SCHEMBL1004267 | 0.81 | LOXL2 (0.64) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 | |
| SCHEMBL4839872 | 0.81 | LOXL2 (0.59) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 | |
| SCHEMBL2041798 | 0.81 | TSHR (0.73) | TSHRHSD17B10LOXL2CYP2A6KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |