Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292554 | 0.93 | LOXL2 (0.58) | LOXL2CYP2A6TSHRHSD17B10CYP19A1 | |
| SCHEMBL8575705 | 0.84 | TSHR (0.59) | LOXL2CYP2A6MMP3TSHRHSD17B10 | |
| SCHEMBL14155434 | 0.81 | LOXL2 (0.58) | LOXL2CYP2A6MMP3TSHRHSD17B10 | |
| SCHEMBL16848648 | 0.81 | LOXL2 (0.58) | LOXL2CYP2A6MMP3TSHRHSD17B10 | |
| SCHEMBL26246 | 0.80 | MMP3 (0.74) | LOXL2CYP2A6MMP3TSHRHSD17B10 | |
| SCHEMBL679947 | 0.80 | HRH3 (0.47) | TSHRHSD17B10CYP19A1HRH3CYP11B2 | |
| SCHEMBL13063633 | 0.80 | MMP3 (0.74) | LOXL2CYP2A6MMP3TSHRHSD17B10 | |
| Water SCHEMBL11055485 | 0.80 | MMP3 (0.74) | LOXL2CYP2A6MMP3TSHRHSD17B10 | |
| SCHEMBL396846 | 0.80 | MMP3 (0.74) | LOXL2CYP2A6MMP3TSHRHSD17B10 | |
| SCHEMBL25300559 | 0.77 | LOXL2 (0.52) | LOXL2CYP2A6MMP3TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |