Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HPN | P05981 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525898 | 0.83 | ALDH1A1 (0.43) | ALOX15HPNMAPTSIRT5ALDH1A1 | |
| SCHEMBL5692047 | 0.81 | ALOX15 (0.55) | ALOX15HPNMAPTSIRT5CA2 | |
| SCHEMBL9190111 | 0.81 | ALOX15 (0.55) | ALOX15HPNMAPTSIRT5CA2 | |
| SCHEMBL8576913 | 0.81 | ALOX15 (0.47) | ALOX15HPNMAPTSIRT5CA2 | |
| SCHEMBL8387741 | 0.79 | ALOX15 (0.53) | ALOX15HPNMAPTSIRT5CA2 | |
| SCHEMBL8577648 | 0.78 | HPN (0.41) | ALOX15HPNMAPTSIRT5CA2 | |
| SCHEMBL9190670 | 0.78 | ALOX15 (0.52) | ALOX15HPNMAPTSIRT5CA2 | |
| SCHEMBL8578891 | 0.78 | ALOX15 (0.52) | ALOX15HPNMAPTSIRT5CA2 | |
| SCHEMBL5692187 | 0.76 | ALOX15 (0.63) | ALOX15HPNMAPTSIRT5CA2 | |
| SCHEMBL646924 | 0.76 | ALOX15 (0.63) | ALOX15HPNMAPTSIRT5CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |