Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521627 | 0.87 | ALDH1A1 (0.41) | HPNMAPTALOX15SIRT5GAA | |
| SCHEMBL8578900 | 0.82 | HPN (0.42) | HPNMAPTALOX15SIRT5MEN1 | |
| SCHEMBL5692124 | 0.82 | HPN (0.45) | HPNMAPTALOX15SIRT5MEN1 | |
| SCHEMBL8579268 | 0.82 | HPN (0.40) | HPNMAPTALOX15SIRT5MEN1 | |
| SCHEMBL8389493 | 0.81 | HPN (0.44) | HPNMAPTALOX15SIRT5MEN1 | |
| SCHEMBL7523211 | 0.79 | ALOX15 (0.39) | MAPTALOX15CYP1A2CYP3A4CYP2C9 | |
| Butyric Acid SCHEMBL27517478 | 0.78 | HSP90AA1 (0.34) | MAPTALOX15GAACYP2C9CYP2C19 | |
| SCHEMBL8576602 | 0.78 | ALOX15 (0.50) | HPNMAPTALOX15SIRT5MEN1 | |
| SCHEMBL8440793 | 0.78 | ESR1 (0.43) | CYP2C9CYP2C19CA2ALDH1A1 | |
| SCHEMBL8578022 | 0.77 | HPN (0.41) | HPNMAPTALOX15SIRT5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |