Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389493 | 0.84 | HPN (0.44) | MEN1KMT2APTGS1PTGS2LMNA | |
| SCHEMBL8577984 | 0.83 | GABRA1 (0.40) | MEN1KMT2ANPC1 | |
| SCHEMBL7520226 | 0.82 | MEN1 (0.36) | MEN1KMT2ANPC1PTGS1PTGS2 | |
| SCHEMBL8439850 | 0.80 | ESR1 (0.42) | MEN1KMT2ANPC1ALOX5ESR1 | |
| SCHEMBL8574791 | 0.80 | MEN1 (0.44) | MEN1KMT2ANPC1PTGS1PTGS2 | |
| SCHEMBL7514795 | 0.77 | ESR1 (0.36) | MEN1KMT2ANPC1ESR1ESR2 | |
| SCHEMBL7526421 | 0.76 | ALDH1A1 (0.39) | LMNAHTT | |
| SCHEMBL8576906 | 0.76 | ESR1 (0.38) | MEN1KMT2ANPC1PTGS1PTGS2 | |
| SCHEMBL8386925 | 0.75 | CYP2C9 (0.41) | MEN1KMT2ANPC1PTGS1PTGS2 | |
| SCHEMBL27516170 | 0.75 | ESR1 (0.38) | ESR1ESR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |