Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516170 | 0.86 | ESR1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL8576997 | 0.83 | MEN1 (0.41) | MEN1NPC1KMT2A | |
| SCHEMBL8389493 | 0.82 | HPN (0.44) | MEN1KMT2A | |
| SCHEMBL8578127 | 0.81 | GABRA1 (0.39) | GABRA1GABRB2SIRT1MEN1NPC1 | |
| SCHEMBL7520582 | 0.78 | ESR1 (0.33) | GABRA1GABRB2MEN1KMT2A | |
| SCHEMBL8439850 | 0.78 | ESR1 (0.42) | MEN1NPC1KMT2A | |
| SCHEMBL8579964 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2 | |
| SCHEMBL7526421 | 0.74 | ALDH1A1 (0.39) | — | |
| SCHEMBL9190822 | 0.72 | GABRA1 (0.39) | GABRA1GABRB2SIRT1 | |
| SCHEMBL8575917 | 0.72 | GABRA1 (0.39) | GABRA1GABRB2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |