Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574961 | 0.91 | MAPT (0.41) | KMT2AALDH1A1MEN1TRPA1EGFR | |
| SCHEMBL8573924 | 0.90 | CDK2 (0.42) | KMT2AALDH1A1MEN1TRPA1EGFR | |
| SCHEMBL8575750 | 0.90 | MAPT (0.41) | KMT2AALDH1A1MEN1TRPA1EGFR | |
| SCHEMBL8573986 | 0.88 | LMNA (0.45) | KMT2AALDH1A1MEN1EGFRMALT1 | |
| SCHEMBL8574333 | 0.88 | EGFR (0.41) | KMT2AALDH1A1MEN1EGFRMAPT | |
| SCHEMBL8576088 | 0.88 | MAPKAPK2 (0.41) | KMT2AALDH1A1MEN1TRPA1EGFR | |
| SCHEMBL8574338 | 0.87 | ALDH1A1 (0.36) | KMT2AALDH1A1MEN1TRPA1EGFR | |
| SCHEMBL8572544 | 0.82 | KMT2A (0.46) | KMT2AALDH1A1MEN1TRPA1EGFR | |
| SCHEMBL8577384 | 0.80 | MALT1 (0.37) | KMT2AALDH1A1MEN1EGFRMALT1 | |
| SCHEMBL8574967 | 0.80 | ALDH1A1 (0.38) | KMT2AALDH1A1MEN1EGFRMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821240-A | ENZYME INHIBITORS, SIGNAL INHIBITORS FOR ANTIINFLAMMATORY AGENTS, ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS AND HORMONE INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1998-10-13 | — | — | US | disclosed |