Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.43 |
| ▸ | QPCT | Q16769 | 7/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571038 | 0.90 | QPCT (0.38) | S1PR1S1PR3S1PR2QPCTQPCTL | |
| SCHEMBL8576418 | 0.87 | FFAR1 (0.38) | QPCTQPCTLFFAR1PPARDPPARA | |
| SCHEMBL8571601 | 0.82 | ITGB3 (0.40) | QPCTQPCTLFFAR1PPARDPPARA | |
| SCHEMBL8571822 | 0.81 | PPARD (0.38) | QPCTQPCTLFFAR1PPARDPPARA | |
| SCHEMBL8573927 | 0.78 | RXRA (0.36) | QPCTQPCTLFFAR1PPARDPPARA | |
| SCHEMBL8576047 | 0.77 | HRH3 (0.38) | QPCTQPCTL | |
| SCHEMBL8414282 | 0.77 | ITGB3 (0.37) | QPCTQPCTLFFAR1PPARDPPARA | |
| SCHEMBL13536889 | 0.77 | S1PR1 (0.66) | S1PR1S1PR3S1PR2FFAR1FFAR4 | |
| SCHEMBL7274915 | 0.76 | S1PR1 (0.54) | S1PR1S1PR3S1PR2FFAR1PPARD | |
| SCHEMBL8416026 | 0.76 | ITGB3 (0.35) | QPCTQPCTLFFAR1PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |