SCHEMBL8577155

SCHEMBL8577155

CCCC[C@@H](NC(=O)OC(C)(C)C)C(N)=O

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSK P43235 19/20 0.65
CTSS P25774 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5967151 1.00 CTSK (0.65) CTSKCTSS
SCHEMBL7977067 1.00 CTSK (0.65) CTSKCTSS
SCHEMBL5615480 0.94 CTSK (0.58) CTSKCTSS
SCHEMBL23677838 0.90 CTSK (0.60) CTSKCTSS
SCHEMBL14302356 0.90 CTSK (0.60) CTSKCTSS
SCHEMBL12890827 0.89 CTSK (0.67) CTSKCTSS
SCHEMBL13385258 0.87 CTSK (0.50) CTSKCTSS
SCHEMBL3244306 0.87 CTSK (0.50) CTSKCTSS
SCHEMBL7837866 0.87 CTSK (0.53) CTSKCTSS
SCHEMBL7837864 0.87 CTSK (0.53) CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736539-A ANITCARCINOGENIC AGENTS MERCK & CO., INC. (US) 1998-04-07 US disclosed
EP-0703905-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO. INC. (US) 1996-04-03 EP disclosed
WO-1995000497-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1995-01-05 WO disclosed