Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13263354 | 0.92 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL28313142 | 0.89 | FOLH1 (0.51) | CTSKCTSSCAPN1MEN1GAA | |
| SCHEMBL11506791 | 0.89 | CTSK (0.49) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL7977067 | 0.87 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL5967151 | 0.87 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL13385258 | 0.87 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL8577155 | 0.87 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL2804552 | 0.86 | CTSK (0.49) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL12015102 | 0.86 | CTSK (0.49) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL5615480 | 0.84 | CTSK (0.58) | CTSKCTSSHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152452-A1 | STEREOSELECTIVE SYNTHESIS OF PIPERIDINE DERIVATIVES | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152452-A1 | STEREOSELECTIVE SYNTHESIS OF PIPERIDINE DERIVATIVES | DHPS, AZI2, DPYD | CTSK 4224/4885CTSS 3427/4885HDAC4 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.