Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.53 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039664 | 0.84 | SRC (0.61) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL10434914 | 0.84 | SRC (0.65) | SRCTLR2ERN1TLR1TLR6 | |
| O-Veratraldehyde SCHEMBL28289918 | 0.82 | SRC (0.67) | SRCTLR2ERN1TLR1TLR6 | |
| O-Veratraldehyde SCHEMBL319070 | 0.82 | SRC (0.67) | SRCTLR2ERN1TLR1TLR6 | |
| O-Veratraldehyde SCHEMBL29923149 | 0.82 | SRC (0.67) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL12904379 | 0.77 | SRC (0.61) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL28023292 | 0.77 | SRC (0.61) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL8007602 | 0.77 | SRC (0.61) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL28463282 | 0.77 | ALDH1A1 (0.53) | SRCTLR2ERN1TLR1TLR6 | |
| O-Veratraldehyde SCHEMBL8706125 | 0.76 | SRC (0.59) | SRCTLR2ERN1TLR1TLR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998009969-A1 | NOVEL ARYL-PYRIDAZINES | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-03-12 | — | — | WO | disclosed |