Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 3/20 | 0.38 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13156749 | 0.88 | EPAS1 (0.38) | KDM4ELMNAPREPNUAK1IGF1R | |
| SCHEMBL8575822 | 0.83 | KDM4E (0.42) | KDM4ELMNANUAK1IGF1RMET | |
| SCHEMBL9053944 | 0.78 | KDM4E (0.39) | KDM4ELMNANUAK1IGF1RMET | |
| SCHEMBL6204130 | 0.73 | KDM4E (0.57) | KDM4ELMNANUAK1IGF1RMET | |
| SCHEMBL12553458 | 0.68 | KDM4E (0.57) | KDM4ELMNANUAK1IGF1RMET | |
| SCHEMBL1660912 | 0.68 | ADRB2 (0.43) | KDM4EPREPCA12CA1CA9 | |
| SCHEMBL29993176 | 0.68 | ADRB2 (0.43) | KDM4EPREPCA12CA1CA9 | |
| SCHEMBL16593838 | 0.68 | PTK2 (0.39) | PREPPTK2 | |
| SCHEMBL30556213 | 0.67 | CA1 (0.38) | PREPCA12CA1CA9ALDH1A1 | |
| SCHEMBL29588862 | 0.66 | ADRB2 (0.52) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849750-A | Dynemicin analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5763451-A | Dynemicin analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-06-09 | — | — | US | disclosed |