Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.76 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171455 | 0.99 | MGLL (0.74) | MGLLCYP4F2CYP4A11BCHEFFAR1 | |
| SCHEMBL1171457 | 0.99 | MGLL (0.74) | MGLLCYP4F2CYP4A11BCHEFFAR1 | |
| SCHEMBL6750228 | 0.99 | MGLL (0.74) | MGLLCYP4F2CYP4A11BCHEFFAR1 | |
| SCHEMBL6410263 | 0.89 | CYP4F2 (0.65) | MGLLCYP4F2CYP4A11BCHEFFAR1 | |
| SCHEMBL1172289 | 0.86 | MGLL (1.00) | MGLLCYP4F2CYP4A11BCHEFFAR1 | |
| SCHEMBL1172084 | 0.86 | MGLL (0.76) | MGLLCYP4F2CYP4A11BCHEFFAR1 | |
| SCHEMBL6752149 | 0.86 | MGLL (0.75) | MGLLBCHEFFAR1 | |
| SCHEMBL1171456 | 0.85 | MGLL (0.74) | MGLLCYP4F2CYP4A11BCHEFFAR1 | |
| SCHEMBL1171728 | 0.85 | MGLL (0.73) | MGLLBCHEFFAR1 | |
| SCHEMBL1172031 | 0.85 | MGLL (0.73) | MGLLBCHEFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912562-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003505-A2 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |