SCHEMBL8577344

SCHEMBL8577344

CCCCC(C(=O)c1ccccc1)C(=O)c1ccc(O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
HSD17B10 Q99714 1/20 0.54
ESR1 P03372 4/20 0.50
HSD17B3 P37058 7/20 0.49
ELANE P08246 1/20 0.48
CTRC Q99895 1/20 0.48
CES2 O00748 2/20 0.47
POLB P06746 1/20 0.47
MDM2 Q00987 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.45
NR1H2 P55055 1/20 0.45
RNASEL Q05823 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PTGS2 P35354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL504212 0.92 MDM2 (0.53) ELANECTRCCES2POLBMDM2
SCHEMBL7066806 0.86 MDM2 (0.52) CES2POLBMDM2SLC6A2SLC6A3
SCHEMBL9356287 0.86 MDM2 (0.52) HSD17B10ELANECTRCCES2POLB
Acetophenone SCHEMBL10488453 0.85 POLB (0.48) LMNAELANECTRCCES2POLB
SCHEMBL30979218 0.85 CES2 (0.53) CES2POLBMDM2SLC6A2SLC6A3
SCHEMBL27836181 0.85 CES2 (0.53) CES2POLBMDM2SLC6A2SLC6A3
SCHEMBL10456426 0.85 CES2 (0.53) CES2POLBMDM2SLC6A2SLC6A3
SCHEMBL1899408 0.83 POLB (0.49) ELANECTRCCES2POLBMDM2
SCHEMBL541916 0.83 CES2 (0.54) LMNACES2POLBSLC6A2SLC6A3
SCHEMBL6386045 0.82 RAB9A (0.50) LMNATSHRMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998013016-A1 STABLE PHOTOPROTECTIVE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-04-02 WO disclosed