Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | CTSG | P08311 | 2/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | CMA1 | P23946 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504212 | 0.93 | MDM2 (0.53) | POLBMDM2CES2CES1PRSS1 | |
| SCHEMBL1899408 | 0.88 | POLB (0.49) | POLBMDM2CES2CES1PRSS1 | |
| SCHEMBL7066806 | 0.88 | MDM2 (0.52) | POLBMDM2CES2CES1PRSS1 | |
| SCHEMBL9356287 | 0.88 | MDM2 (0.52) | POLBMDM2CES2CES1PRSS1 | |
| SCHEMBL10456426 | 0.86 | CES2 (0.53) | POLBMDM2CES2CES1PRSS1 | |
| SCHEMBL27836181 | 0.86 | CES2 (0.53) | POLBMDM2CES2CES1PRSS1 | |
| SCHEMBL30979218 | 0.86 | CES2 (0.53) | POLBMDM2CES2CES1PRSS1 | |
| SCHEMBL8577344 | 0.85 | LMNA (0.54) | POLBMDM2CES2CES1PRSS1 | |
| SCHEMBL11528495 | 0.83 | CES2 (0.47) | POLBMDM2CES2CES1PRSS1 | |
| SCHEMBL9352547 | 0.83 | CES2 (0.50) | POLBMDM2CES2CES1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814162-A | SUNSCREENS | L'OREAL (FR) | 1989-03-21 | — | — | US | disclosed |