Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HEXA | P06865 | 1/20 | 0.36 |
| ▸ | HEXB | P07686 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431713 | 0.77 | CNR1 (0.48) | NPSR1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL8576743 | 0.74 | ALDH1A1 (0.46) | NPSR1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL8796992 | 0.73 | HPGD (0.42) | NPSR1ALDH1A1SMN1; SMN2POLBRAB9A | |
| SCHEMBL11376573 | 0.73 | ALDH1A1 (0.51) | NPSR1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL8624518 | 0.72 | CES1 (0.43) | NPSR1HTTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8578690 | 0.71 | MAOA (0.38) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8578688 | 0.70 | HTT (0.32) | NPSR1HTT | |
| SCHEMBL28631453 | 0.67 | HEXA (0.40) | NPSR1ALDH1A1MEN1CYP1A2CYP2D6 | |
| SCHEMBL8576377 | 0.67 | KDM4E (0.40) | ALDH1A1KMT2AHEXAHEXBRAB9A | |
| SCHEMBL11403812 | 0.66 | POLB (0.52) | NPSR1ALDH1A1MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710152-A | ANTIDIABETIC, ANTILIPEMIC, AND HYPOGLYCEMIC AGENTS; DIETETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |