Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8578750 | 0.88 | F2 (0.49) | F2F10PLAU | |
| SCHEMBL8580938 | 0.76 | ACACB (0.48) | ACACBF2F10PLAUALDH1A1 | |
| SCHEMBL13538761 | 0.74 | ACACB (0.64) | ACACBF2F10ALDH1A1TGFBR1 | |
| SCHEMBL8580939 | 0.70 | ACACB (0.43) | ACACBF2F10PLAUALDH1A1 | |
| SCHEMBL10194537 | 0.69 | SFRP1 (0.53) | ACACBALDH1A1TGFBR1USP30SFRP1 | |
| SCHEMBL10194504 | 0.69 | ACACB (0.59) | ACACBF10TGFBR1 | |
| SCHEMBL10194489 | 0.69 | ACACB (0.71) | ACACBTGFBR1 | |
| SCHEMBL6340184 | 0.68 | ACACB (0.52) | ACACBF2ALDH1A1HTR1AADRA2A | |
| SCHEMBL10194533 | 0.67 | HTR7 (0.63) | ALDH1A1HTR1AADRA2A | |
| SCHEMBL10194548 | 0.66 | SFRP1 (0.56) | ACACBALDH1A1TGFBR1SFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763436-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |