Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 6/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580938 | 0.81 | ACACB (0.48) | ACACBF2F10PLAUMMP1 | |
| SCHEMBL13538761 | 0.77 | ACACB (0.64) | ACACBF2F10TGFBR1ALDH1A1 | |
| SCHEMBL10194537 | 0.73 | SFRP1 (0.53) | ACACBSTSTGFBR1ALDH1A1 | |
| SCHEMBL10194504 | 0.71 | ACACB (0.59) | ACACBF10TGFBR1 | |
| SCHEMBL10194548 | 0.71 | SFRP1 (0.56) | ACACBSTSTGFBR1ALDH1A1 | |
| SCHEMBL10194498 | 0.71 | ADAM17 (0.51) | ACACBF10STSTGFBR1 | |
| SCHEMBL10194489 | 0.71 | ACACB (0.71) | ACACBTGFBR1 | |
| SCHEMBL2333096 | 0.70 | STS (0.45) | ACACBSTSALDH1A1 | |
| SCHEMBL8577423 | 0.70 | ACACB (0.41) | ACACBF2F10PLAUTGFBR1 | |
| SCHEMBL7299431 | 0.69 | F2 (0.62) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763436-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |