Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | JUN | P05412 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566570 | 0.82 | TSHR (0.36) | KDM4EALDH1A1 | |
| SCHEMBL8558079 | 0.79 | POLB (0.35) | KDM4EALDH1A1KEAP1NFE2L2JUN | |
| SCHEMBL8566197 | 0.75 | NFKB1 (0.35) | KEAP1NFE2L2JUNNFKB1NFKB2 | |
| SCHEMBL8560094 | 0.74 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL8565949 | 0.73 | NR4A1 (0.41) | ALDH1A1 | |
| SCHEMBL26598773 | 0.69 | — | — | |
| SCHEMBL8176734 | 0.69 | POLB (0.36) | — | |
| SCHEMBL30843825 | 0.68 | GSK3B (0.37) | PTPN1GSK3BP2RX7 | |
| SCHEMBL8566402 | 0.65 | APLNR (0.33) | — | |
| SCHEMBL3921448 | 0.65 | GSK3B (0.41) | PTPN1GSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773388-A | Pyrimidine derivatives, herbicides and plant growth regulators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0713872-A1 | NOVEL PYRIMIDINE DERIVATIVE, HERBICIDE AND PLANT GROWTH REGULATOR | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-05-29 | — | — | EP | disclosed |