Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012918 | 0.74 | HCAR2 (0.39) | L3MBTL1ALOX15KMT2AHPGDTHRB | |
| SCHEMBL8576768 | 0.73 | ADORA1 (0.44) | NPC1RAB9AMAPK1KMT2AHPGD | |
| SCHEMBL29387256 | 0.73 | CYP3A4 (0.55) | ALPLTP53HTTKMT2AHPGD | |
| SCHEMBL333141 | 0.73 | CYP3A4 (0.55) | ALPLTP53HTTKMT2AHPGD | |
| SCHEMBL8580209 | 0.73 | DGAT1 (0.33) | NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL22907602 | 0.73 | SIRT3 (0.42) | L3MBTL1 | |
| SCHEMBL10669335 | 0.71 | CYP3A4 (0.59) | ALPLTP53HTTKMT2AHPGD | |
| SCHEMBL8581181 | 0.68 | MGLL (0.36) | L3MBTL1KMT2A | |
| SCHEMBL8577603 | 0.68 | GAA (0.47) | ALOX15KMT2A | |
| SCHEMBL1106088 | 0.67 | DGAT1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773388-A | Pyrimidine derivatives, herbicides and plant growth regulators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0713872-A1 | NOVEL PYRIMIDINE DERIVATIVE, HERBICIDE AND PLANT GROWTH REGULATOR | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-05-29 | — | — | EP | disclosed |