Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566193 | 0.84 | SYK (0.34) | KDM4ESYK | |
| SCHEMBL1012918 | 0.83 | HCAR2 (0.39) | DGAT1KDM4EMAPTTDP1 | |
| SCHEMBL22907602 | 0.81 | SIRT3 (0.42) | DGAT1SYKTDP1 | |
| SCHEMBL1012427 | 0.75 | KDM4E (0.49) | KDM4ENPC1MAPTNFKB1RAB9A | |
| SCHEMBL8577797 | 0.73 | TYK2 (0.40) | NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL8576768 | 0.73 | ADORA1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31505058 | 0.70 | DGAT1 (0.34) | DGAT1KDM4EMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL8579235 | 0.69 | CYP1A2 (0.42) | KDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL13610835 | 0.69 | HSD17B10 (0.47) | KDM4ESYKSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL13663613 | 0.69 | HSD11B1 (0.47) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773388-A | Pyrimidine derivatives, herbicides and plant growth regulators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0713872-A1 | NOVEL PYRIMIDINE DERIVATIVE, HERBICIDE AND PLANT GROWTH REGULATOR | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-05-29 | — | — | EP | disclosed |