SCHEMBL8578237

SCHEMBL8578237

CCC(c1ccc(C#N)cc1)c1ccc(C(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.48
SLC6A3 Q01959 1/20 0.47
GSK3B P49841 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
AR P10275 1/20 0.45
ALDH1A1 P00352 2/20 0.44
TAS2R14 Q9NYV8 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PTGER4 P35408 2/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
CYP2J2 P51589 1/20 0.43
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11770487 0.87 EPHX2 (0.52) EPHX2SLC6A3GSK3BCA1CA2
SCHEMBL28613441 0.86 CYP2A6 (0.52) EPHX2CA2MAPTKDM4EGAA
SCHEMBL938192 0.86 ALDH1A1 (0.56) CA1CA2MAPTALDH1A1KMT2A
SCHEMBL8861254 0.83 GSK3B (0.49) EPHX2GSK3BCA1CA2MAPT
SCHEMBL11768884 0.82 TP53 (0.49) EPHX2SLC6A3MAPTALDH1A1MEN1
SCHEMBL216706 0.82 CA2 (0.64) GSK3BCA1CA2MAPTAR
SCHEMBL23882872 0.81 SRD5A2 (0.53) EPHX2GSK3BCA1CA2MAPT
SCHEMBL9641685 0.80 TSHR (0.50) MAPTKDM4EGAAL3MBTL1ALDH1A1
SCHEMBL17071854 0.80 TSHR (0.50) MAPTKDM4EGAAL3MBTL1ALDH1A1
SCHEMBL27344332 0.80 LMNA (0.50) MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10112333-A None JP disclosed
US-5833879-A LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES CHISSO CORPORATION (JP) 1998-11-10 US disclosed
US-5779936-A FLUORINATED BICYCLOHEXANE OR CYCLOHEXYLETHYL CYCLOHEXANE DERIVATIVE HAVING LOW VISCOSITY AND HIGH CLEARING POINT TEMPERATURE CHISSO CORPORATION (JP) 1998-07-14 US disclosed
JP-H10112333-A NONAQUEOUS ELECTROLYTE SECONDARY BATTERY DENSO CORP 1998-04-28 JP disclosed