Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29625674 | 0.83 | HSD17B10 (0.57) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL9294181 | 0.83 | HSD17B10 (0.57) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL10751032 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL11842789 | 0.79 | HSD17B10 (0.46) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL11841719 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL1161044 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL2162162 | 0.79 | IMPDH2 (0.61) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL2552536 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL20561943 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL6640971 | 0.76 | HTR2A (0.48) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |