Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611288 | 0.84 | HTR2A (0.52) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD | |
| SCHEMBL28248009 | 0.81 | HTR2A (0.48) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD | |
| SCHEMBL1169916 | 0.79 | HTR2A (0.60) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD | |
| SCHEMBL28499383 | 0.78 | HTR2A (0.46) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD | |
| SCHEMBL8579502 | 0.76 | ALDH1A1 (0.46) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD | |
| SCHEMBL29463710 | 0.74 | ALDH1A1 (0.48) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD | |
| SCHEMBL677653 | 0.74 | ALDH1A1 (0.48) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD | |
| SCHEMBL31281983 | 0.74 | ALDH1A1 (0.48) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD | |
| SCHEMBL3744215 | 0.74 | HTR2A (0.42) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD | |
| SCHEMBL3669260 | 0.74 | ALDH1A1 (0.43) | HTR2AL3MBTL1ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377577-A1 | PYRROLE DERIVATES FOR TREATING CYTOKINE MEDIATED DISEASES | Sankyo Company Limited (JP) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002057264-A1 | PYRROLE DERIVATES FOR TREATING CYTOKINE MEDIATED DISEASES | SANKYO COMPANY LIMITED (JP) | 2002-07-25 | — | — | WO | disclosed |