Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582603 | 0.88 | KDM4E (0.38) | KDM4EMAPTPDGFRBPDGFRAPTGS2 | |
| SCHEMBL8482345 | 0.82 | SLC10A2 (0.38) | KDM4EMAPTPDGFRBPDGFRARAB9A | |
| SCHEMBL8581223 | 0.81 | MAPK1 (0.36) | KDM4EMAPTPDGFRBPDGFRAPTGS2 | |
| SCHEMBL8477185 | 0.80 | KDM4E (0.38) | KDM4EMAPTPDGFRBPDGFRAPTGS2 | |
| SCHEMBL8583197 | 0.80 | PTGS2 (0.35) | KDM4EMAPTPDGFRBPDGFRAPTGS2 | |
| SCHEMBL8479712 | 0.79 | MAPT (0.39) | KDM4EMAPTPDGFRBPDGFRAPTGS2 | |
| SCHEMBL8478485 | 0.77 | MGAM (0.36) | KDM4EMAPTPDGFRBPDGFRAPTGS2 | |
| SCHEMBL8477623 | 0.76 | NPC1 (0.36) | KDM4EMAPTPDGFRBPDGFRAPTGS2 | |
| SCHEMBL8478190 | 0.75 | KDM4E (0.35) | KDM4EMAPTPDGFRBPDGFRAPTGS2 | |
| SCHEMBL8478177 | 0.74 | PTGS2 (0.39) | MAPTPTGS2RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |