Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | SI | P14410 | 6/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474433 | 0.90 | MGAM (0.39) | MGAMGAASIMGAM2EPHX2 | |
| SCHEMBL8480653 | 0.82 | SLC10A2 (0.39) | SLC10A2FFAR1PTGS2HTTNPSR1 | |
| SCHEMBL8581223 | 0.81 | MAPK1 (0.36) | MGAMGAASIMGAM2SLC10A2 | |
| SCHEMBL8474699 | 0.81 | MAPT (0.37) | MGAMGAASIMGAM2SLC10A2 | |
| SCHEMBL8480085 | 0.80 | PDE4B (0.38) | MGAMGAASIMGAM2PDE4A | |
| SCHEMBL8583197 | 0.80 | PTGS2 (0.35) | MGAMGAASIMGAM2SLC10A2 | |
| SCHEMBL8478465 | 0.78 | KDM4E (0.35) | SLC10A2FFAR1PTGS2HTTNPSR1 | |
| SCHEMBL8474318 | 0.78 | ESR2 (0.41) | MGAMGAASIMGAM2PTGS2 | |
| SCHEMBL8580141 | 0.77 | KDM4E (0.38) | MGAMGAASIMGAM2SLC10A2 | |
| SCHEMBL8475146 | 0.77 | MGAM (0.42) | MGAMGAASIMGAM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |