Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453251 | 0.89 | TDP1 (0.39) | SMN1; SMN2ALDH1A1CYP3A4TSHRMEN1 | |
| SCHEMBL5384886 | 0.89 | PYCR1 (0.34) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL9260850 | 0.89 | TSHR (0.35) | SMN1; SMN2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL3260092 | 0.84 | CA2 (0.42) | TSHRCA1CA2CA7 | |
| SCHEMBL3260026 | 0.80 | CA2 (0.40) | TSHRCA1CA2 | |
| SCHEMBL2166944 | 0.78 | LTA4H (0.33) | SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL3808515 | 0.72 | — | — | |
| SCHEMBL5405196 | 0.70 | TSHR (0.35) | SMN1; SMN2ALDH1A1CYP3A4TSHRMEN1 | |
| SCHEMBL1427919 | 0.70 | TSHR (0.35) | SMN1; SMN2ALDH1A1CYP3A4TSHRMEN1 | |
| SCHEMBL9265706 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909301-A1 | BIODEGRADABLE LIQUID CRYSTALLINE POLYMERS | Smith & Nephew plc (GB) | 1999-04-21 | — | — | EP | disclosed |
| WO-1997048782-A1 | BIODEGRADABLE LIQUID CRYSTALLINE POLYMERS | SMITH & NEPHEW PLC (GB) | 1997-12-24 | — | — | WO | disclosed |