Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 4/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CBR1 | P16152 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072347 | 0.91 | TTR (0.52) | CHRM1MAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1678635 | 0.86 | L3MBTL1 (0.55) | MAPTHPGDSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9799896 | 0.86 | L3MBTL1 (0.55) | MAPTHPGDSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1037978 | 0.84 | CHRM1 (0.57) | CHRM1MAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL15546827 | 0.81 | ALOX15 (0.58) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL8332048 | 0.81 | FFAR1 (0.57) | CHRM1MAPTSLC6A2SLC6A3TTR | |
| SCHEMBL28731975 | 0.80 | CHRM1 (0.56) | CHRM1MAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8743430 | 0.78 | TTR (0.51) | CHRM1MAPTSLC6A2SLC6A3PLA2G1B | |
| SCHEMBL2118037 | 0.78 | TTR (0.51) | CHRM1MAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8435546 | 0.78 | ALOX15 (0.55) | MAPTHPGDSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798316-A | GRASS OR BROADLEAF CONTROLLING AGENTS | FMC CORPORATION | 1998-08-25 | — | — | US | disclosed |
| US-5753595-A | Herbicidal 3-(substituted benzoxazol-7-yl) and 3-(Substituted benzothiazol-7-yl)-1-substituted-6-trifluoromethyl-2 4-(1h 3h)pyrimidinediones | FMC CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| US-5683966-A | Herbicidal 3-(substituted-benzyl)-1-methyl-6-trifluoromethyluracils | FMC CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5674810-A | MIXTURE OF TWO HERBICIDES WITH DIFFERENT STRUCTURES, CARRIER | FMC CORPORATION (US) | 1997-10-07 | — | — | US | disclosed |