Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489385 | 0.91 | LDHA (0.38) | LDHASRRTSHR | |
| SCHEMBL27532276 | 0.89 | LDHA (0.36) | LDHASRRTSHR | |
| SCHEMBL16431049 | 0.79 | MGAM (0.33) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL28148318 | 0.78 | — | — | |
| SCHEMBL28120209 | 0.76 | — | — | |
| SCHEMBL28323922 | 0.76 | MGAM (0.50) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL16431069 | 0.75 | GAA (0.62) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL26907179 | 0.74 | EGLN1 (0.41) | TSHR | |
| Butane SCHEMBL1060217 | 0.72 | FFAR3 (0.33) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butane SCHEMBL6666677 | 0.72 | MGAM (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998009973-A9 | BORON-CONTAINING AMINO CARBOXYLIC ACID COMPOUNDS AND USES THEREOF | — | 1998-07-30 | — | — | WO | disclosed |
| WO-1998009973-A1 | BORON-CONTAINING AMINO CARBOXYLIC ACID COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 1998-03-12 | — | — | WO | disclosed |
| EP-0364996-A2 | Phosphono-hydroisoquinoline compounds useful in reducing neurotoxic injury | G.D. Searle & Co. (US) | 1990-04-25 | — | — | EP | disclosed |