SCHEMBL28323922

SCHEMBL28323922

CC(=O)CC(=O)ONC=O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.50
GAA P10253 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
HTT P42858 1/20 0.31
TSHR P16473 1/20 0.31
KDM4E B2RXH2 1/20 0.30
KDM6B O15054 1/20 0.30
KDM5C P41229 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16431049 0.85 MGAM (0.33) MGAMGAASIMGAM2TSHR
SCHEMBL11791161 0.82 ALDH1A1 (0.43) MGAMGAASIMGAM2TSHR
SCHEMBL28314137 0.78
SCHEMBL9489385 0.78 LDHA (0.38) TSHRKDM4E
SCHEMBL28120209 0.76
SCHEMBL27532276 0.76 LDHA (0.36) TSHRKDM4E
Butane SCHEMBL8580310 0.76 FFAR3 (0.32) MGAMGAASIMGAM2TSHR
SCHEMBL10694019 0.74
SCHEMBL28148318 0.74
SCHEMBL1342561 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946022-A Synthesis method of hymexazol 青岛锐丰源化工有限公司 2024-04-30 CN claimed
CN-117946022-A Synthesis method of hymexazol 青岛锐丰源化工有限公司 2024-04-30 CN disclosed
CN-106164072-B Monocyclic lactam organic compounds for the treatment of bacterial infections 诺华股份有限公司 2019-10-01 CN disclosed