Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580305 | 0.89 | MAPT (0.47) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL7819889 | 0.83 | CA12 (0.46) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL7201067 | 0.78 | TSHR (0.50) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL8580296 | 0.72 | MAOB (0.49) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL7823936 | 0.71 | CA12 (0.46) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL10455857 | 0.71 | CA12 (0.63) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL5337504 | 0.70 | PTGS2 (0.47) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL1519218 | 0.68 | TDP1 (0.57) | MAPTNPC1RAB9AL3MBTL1GAA | |
| SCHEMBL28840933 | 0.68 | — | — | |
| SCHEMBL30786817 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807882-A | ANTITUMOR AGENTS | ADIR ET COMPAGNIE (FR) | 1998-09-15 | — | — | US | disclosed |