Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337504 | 0.84 | PTGS2 (0.47) | TSHRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9251348 | 0.81 | CA12 (0.49) | TSHRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8580093 | 0.81 | CA12 (0.49) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL30606875 | 0.81 | MTNR1A (0.46) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL8580296 | 0.80 | MAOB (0.49) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL8579581 | 0.79 | KDM4E (0.48) | TSHRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8580456 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8580159 | 0.78 | MAPT (0.39) | TSHRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8580415 | 0.78 | MAPT (0.47) | TSHRMAPTKMT2AMEN1CA12 | |
| SCHEMBL8580305 | 0.78 | MAPT (0.47) | TSHRMAPTKMT2AMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10139779-A | — | — | None | — | — | JP | disclosed |
| US-6602903-B2 | Substituted O- and/or S heterocyclic compounds; powerful ligands for melatoninergic receptors. | LES LABORATORIES SERVIER (FR) | 2003-08-05 | — | — | US | disclosed |
| US-20020052400-A1 | Substituted heterocyclic compounds | ADIR ET COMPAGNIE | 2002-05-02 | — | — | US | disclosed |
| US-6313160-B1 | FOR THERAPY AND PROPHYLAXIS OF MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-11-06 | — | — | US | disclosed |
| US-5807882-A | ANTITUMOR AGENTS | ADIR ET COMPAGNIE (FR) | 1998-09-15 | — | — | US | disclosed |
| JP-H10139779-A | SUBSTITUTED 7,12-DIOXABENZO(A)ANTHRACENE COMPOUND, PRODUCTION THEREOF AND MEDICINAL COMPOSITION CONTAINING THE SAME | ADIR | 1998-05-26 | — | — | JP | disclosed |
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| WO-1981003172-A1 | NOVEL BENZO(1,4)DIOXINS,METHODS FOR THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | CERM CENT EUROP RECH MAUVERNAY (FR) | 1981-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052400-A1 | Substituted heterocyclic compounds | MTNR1A, MTNR1B, CBR1 | TSHR 263/4885ALDH1A1 486/4885MAPT 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.