Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579581 | 0.87 | KDM4E (0.48) | ALDH1A1HPGDKDM4ECA12CA2 | |
| SCHEMBL8580159 | 0.86 | MAPT (0.39) | MAOBALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL9255645 | 0.85 | CA12 (0.47) | ALDH1A1HPGDKDM4ECA12CA2 | |
| SCHEMBL8580093 | 0.84 | CA12 (0.49) | MAOBALDH1A1HPGDCA12CA2 | |
| SCHEMBL9257011 | 0.83 | KDM4E (0.47) | ALDH1A1HPGDKDM4ECA12CA2 | |
| SCHEMBL7819674 | 0.82 | KDM4E (0.44) | ALDH1A1HPGDKDM4ECA12CA2 | |
| SCHEMBL8580456 | 0.82 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4ECA12CA2 | |
| SCHEMBL5337504 | 0.81 | PTGS2 (0.47) | MAOBALDH1A1HPGDKDM4EGLA | |
| SCHEMBL7201067 | 0.80 | TSHR (0.50) | ALDH1A1KDM4ECA12CA2GLA | |
| SCHEMBL9251348 | 0.78 | CA12 (0.49) | MAOBALDH1A1HPGDCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807882-A | ANTITUMOR AGENTS | ADIR ET COMPAGNIE (FR) | 1998-09-15 | — | — | US | disclosed |