Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579581 | 0.83 | KDM4E (0.48) | ALDH1A1CA12CA2CA9MAPT | |
| SCHEMBL8580093 | 0.83 | CA12 (0.49) | ALDH1A1MAPK1CA12CA1CA2 | |
| SCHEMBL8580296 | 0.82 | MAOB (0.49) | ALDH1A1L3MBTL1CA12CA2CA7 | |
| SCHEMBL7819754 | 0.81 | KDM4E (0.44) | ALDH1A1MAPK1L3MBTL1MAPTRAB9A | |
| SCHEMBL9257011 | 0.80 | KDM4E (0.47) | ALDH1A1CA12CA2CA9MAPT | |
| SCHEMBL7201067 | 0.79 | TSHR (0.50) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL9251348 | 0.77 | CA12 (0.49) | ALDH1A1MAPK1CA12CA1CA2 | |
| SCHEMBL4621893 | 0.73 | CA12 (0.56) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| SCHEMBL9259734 | 0.72 | KDM4E (0.36) | ALDH1A1MAPK1L3MBTL1CA12CA1 | |
| SCHEMBL9258943 | 0.72 | KDM4E (0.36) | ALDH1A1MAPK1L3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807882-A | ANTITUMOR AGENTS | ADIR ET COMPAGNIE (FR) | 1998-09-15 | — | — | US | disclosed |
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |