Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259734 | 1.00 | KDM4E (0.36) | KDM4ENPC1RAB9AHSD17B10ALDH1A1 | |
| SCHEMBL9254765 | 0.83 | SMN1; SMN2 (0.38) | KDM4EALDH1A1HPGDNPSR1HTT | |
| SCHEMBL9258671 | 0.83 | SMN1; SMN2 (0.38) | KDM4EALDH1A1HPGDNPSR1HTT | |
| SCHEMBL9257011 | 0.79 | KDM4E (0.47) | KDM4ENPC1ALDH1A1HPGDNPSR1 | |
| SCHEMBL8580456 | 0.72 | ALDH1A1 (0.41) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL9251348 | 0.71 | CA12 (0.49) | HSD17B10ALDH1A1HPGDNPSR1HTT | |
| SCHEMBL5337504 | 0.71 | PTGS2 (0.47) | KDM4ENPC1RAB9AHSD17B10ALDH1A1 | |
| SCHEMBL8580296 | 0.70 | MAOB (0.49) | KDM4ENPC1RAB9AHSD17B10ALDH1A1 | |
| SCHEMBL9263059 | 0.69 | CYP4F2 (0.42) | NPC1ALDH1A1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL8580159 | 0.69 | MAPT (0.39) | KDM4ENPC1RAB9AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |