Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583413 | 0.92 | TBXAS1 (0.52) | TBXAS1PTGDR2KDM4E | |
| SCHEMBL8583157 | 0.83 | TBXAS1 (0.56) | TBXAS1PTGDR2MEN1KMT2AKDM4E | |
| SCHEMBL8580490 | 0.82 | TBXAS1 (0.61) | TBXAS1PTGDR2 | |
| SCHEMBL8583156 | 0.77 | TBXAS1 (0.64) | TBXAS1PTGDR2 | |
| SCHEMBL8542545 | 0.77 | TBXAS1 (0.88) | TBXAS1PTGDR2 | |
| SCHEMBL8545966 | 0.74 | TBXAS1 (0.78) | TBXAS1PTGDR2 | |
| SCHEMBL8583155 | 0.74 | TBXAS1 (0.55) | TBXAS1PTGDR2SMN1; SMN2 | |
| SCHEMBL8541824 | 0.73 | TBXAS1 (0.67) | TBXAS1PTGDR2 | |
| Water SCHEMBL11291624 | 0.71 | PTGDR2 (0.73) | TBXAS1PTGDR2KDM4E | |
| SCHEMBL8538829 | 0.71 | TBXAS1 (0.59) | TBXAS1PTGDR2MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | claimed |