Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749760 | 0.91 | SLC9A1 (0.54) | SLC9A1VCAM1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8580952 | 0.85 | GAA (0.46) | KDM4ESMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL8573449 | 0.85 | CA2 (0.41) | SLC9A1VCAM1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL2912709 | 0.85 | KDM4E (0.46) | SLC9A1VCAM1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8581950 | 0.85 | ALDH1A1 (0.40) | SLC9A1VCAM1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL2968143 | 0.85 | SLC9A1 (0.42) | SLC9A1VCAM1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL1763859 | 0.85 | SLC9A1 (0.42) | SLC9A1VCAM1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8045262 | 0.85 | SLC9A1 (0.42) | SLC9A1VCAM1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6922302 | 0.85 | MAPT (0.45) | SLC9A1VCAM1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8583500 | 0.83 | SLC9A1 (0.41) | SLC9A1VCAM1KDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |