Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 14/20 | 0.53 |
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | CD74 | P04233 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578797 | 0.90 | EDNRB (0.67) | EDNRB | |
| SCHEMBL8798914 | 0.87 | EDNRB (0.53) | EDNRBLMNAMAPT | |
| SCHEMBL8798232 | 0.87 | EDNRB (0.52) | EDNRB | |
| SCHEMBL8575986 | 0.78 | EDNRB (0.65) | EDNRB | |
| SCHEMBL8798383 | 0.77 | EDNRB (0.77) | EDNRBMAPT | |
| SCHEMBL8580666 | 0.76 | EDNRB (0.63) | EDNRB | |
| SCHEMBL8798379 | 0.72 | EDNRB (0.81) | EDNRBMAPT | |
| SCHEMBL8798255 | 0.71 | EDNRB (0.79) | EDNRBMAPT | |
| SCHEMBL8798910 | 0.70 | EDNRB (0.73) | EDNRBMAPT | |
| SCHEMBL8798982 | 0.69 | EDNRB (0.78) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757039-A1 | Endothelin receptor antagonists | MERCK PATENT GmbH (DE) | 1997-02-05 | — | — | EP | disclosed |