Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 6/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580666 | 0.90 | EDNRB (0.63) | EDNRBSERPINE1 | |
| SCHEMBL8798447 | 0.87 | EDNRB (0.53) | EDNRB | |
| SCHEMBL8798914 | 0.85 | EDNRB (0.53) | EDNRBMEN1KMT2A | |
| SCHEMBL8578797 | 0.76 | EDNRB (0.67) | EDNRB | |
| SCHEMBL8575986 | 0.75 | EDNRB (0.65) | EDNRB | |
| SCHEMBL8798383 | 0.75 | EDNRB (0.77) | EDNRBMEN1KMT2A | |
| SCHEMBL8798379 | 0.70 | EDNRB (0.81) | EDNRB | |
| SCHEMBL8553066 | 0.69 | EDNRB (0.43) | EDNRBMEN1KMT2A | |
| SCHEMBL8798255 | 0.69 | EDNRB (0.79) | EDNRB | |
| SCHEMBL8804652 | 0.68 | EDNRB (1.00) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811001-A1 | BENZOTHIAZINE DIOXIDES AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-12-10 | — | — | EP | claimed |