Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582487 | 0.92 | HTT (0.38) | HTTGAAKDM4ENPSR1KMT2A | |
| SCHEMBL8581512 | 0.89 | KDM4E (0.43) | HTTGAAKDM4ENPSR1KMT2A | |
| SCHEMBL8582018 | 0.86 | SLC9A1 (0.45) | HTTGAAKDM4ENPSR1KMT2A | |
| SCHEMBL8583830 | 0.85 | SLC9A1 (0.45) | KDM4EKMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL8583320 | 0.85 | KDM4E (0.36) | KDM4EKMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL8581991 | 0.84 | KDM4E (0.41) | HTTGAAKDM4ENPSR1KMT2A | |
| SCHEMBL8580504 | 0.84 | KMT2A (0.38) | KDM4ENPSR1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL8583730 | 0.84 | ALDH1A1 (0.35) | KDM4EKMT2AHSD17B10ALDH1A1POLB | |
| SCHEMBL8585521 | 0.82 | KDM4E (0.40) | HTTGAAKDM4ENPSR1KMT2A | |
| SCHEMBL8585498 | 0.82 | PPARG (0.36) | KDM4EKMT2AHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |