Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580999 | 0.92 | CA2 (0.35) | KMT2ACA2CA1CA5ACA9 | |
| SCHEMBL8585573 | 0.89 | KMT2A (0.38) | KMT2ACA2CA1CA5ACA9 | |
| SCHEMBL8583320 | 0.85 | KDM4E (0.36) | KMT2ACA2CA1CA5ACA9 | |
| SCHEMBL8583830 | 0.85 | SLC9A1 (0.45) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8580704 | 0.84 | HTT (0.41) | KMT2AKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8583730 | 0.84 | ALDH1A1 (0.35) | KMT2ACA2CA1CA5ACA9 | |
| SCHEMBL8585498 | 0.82 | PPARG (0.36) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8585093 | 0.80 | VCAM1 (0.50) | KMT2AALDH1A1LMNAMAPTVCAM1 | |
| SCHEMBL8583706 | 0.79 | CA2 (0.46) | KMT2ACA2CA1CA5ACA9 | |
| SCHEMBL8533438 | 0.78 | SLC9A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |